A Guide to Female Sexual Dysfunction Treatments

However, it’s currently unknown how well it works on all ingredients, and the effect may be inconsistent on some.87 As with most supplements and medications, there are some safety risks to keep in mind. For Libido Lift Rx and Drive For Her, they include: Both products (and O-Cream Rx) are unsafe for individuals who are pregnant or nursing. Tadalafil can lead to headaches, indigestion, back pain, nasal congestion, hypotension, skin flushing, limb pain, nausea, dizziness, vision changes, hearing loss, and rashes.64 Tadalafil may interact with alcohol, alpha-blockers, antihypertensives, and other medications.64 Fenugreek (Libifem) may be unsafe for those with thyroid or hormone-sensitive concerns.88 89 Reishi may interact with medications for diabetes, blood pressure, and blood clotting.90 Saffron shouldn’t be taken by those with diabetes, hypoglycemia, low blood pressure, or bipolar disorder. It may also interact with sedatives, antidepressants, and more.91 Of course, the list above isn’t comprehensive, so you should always speak with your doctor before adding a new supplement or prescription to your routine. It’s worth mentioning that Cake Meds For Her can’t be shipped to Alabama, California, South Carolina, Guam, or Puerto Rico due to restrictions. This means that those territories can’t get Libido Lift Rx or O-Cream Rx, but they can still get the Drive For Her supplement. In contrast, Wisp is able to prescribe medications in all 50 U.S.

• There is no true over-the-counter "female Viagra" available in UK pharmacies.
• Viagra (sildenafil) is licensed for men and is not approved for female sexual dysfunction.
• Some online sources may illegally sell prescription-only medications without consultation.
• Herbal libido supplements are available OTC but are not proven to be effective.
• Lubricants and moisturizers are widely available OTC without a prescription.
• Buying prescription medicine without a prescription is illegal and potentially dangerous.
• Always obtain medications through a legitimate consultation with a qualified prescriber.

states, so you can get OMG! Cream no matter where you are viagra daily in the country. The chart below breaks down the pricing details for Libido Lift Rx, Drive For Her, and O-Cream Rx (regular and extra strength). As you can see, Cake’s prescription products can’t be purchased on a one-time basis.

• A GP is the first point of contact for discussing sexual health concerns in the UK.
• They may conduct blood tests to check hormone levels (e.g., testosterone, estrogen).
• A full medical and psychological history is essential for an accurate diagnosis.
• GPs can refer patients to a specialist clinic, like a urogynaecology or sexual health service.
• Specialists may work in NHS hospitals or private practices.
• The British Society for Sexual Medicine provides guidelines for healthcare professionals.
• A diagnosis often involves ruling out other medical and relationship issues first.

This means that you’ll have to sign up for a recurring subscription if you’re interested in either of those. Drive For Her, on the other hand, can be purchased either way, and it’s covered under the company’s 30-day satisfaction guarantee.

• Flibanserin works on neurotransmitters in the brain, increasing dopamine and noradrenaline.
• It simultaneously decreases serotonin activity, which is thought to inhibit sexual desire.
• Bremelanotide is a melanocortin receptor agonist that acts on pathways in the brain.
• Ospemifene is a Selective Estrogen Receptor Modulator (SERM) with estrogen-like effects.
• Testosterone is thought to play a key role in libido for both men and women.
• Topical estrogens work by replenishing thinning vaginal tissues.
• Understanding the mechanism helps in choosing the right treatment for the cause.

Around 100 treatments per bottle if used as directed Peppermint oil and damiana may promote arousal Should be safe for pregnant individuals (still check with your doctor, though) Not recommended for people with genital herpes due to L-arginine content No guarantee available and refunds are only for unopened products Some people may not like the warming, yet cold and minty sensation Unbound (also known as “Unbound Babes”) is a sexual wellness company that is, in its own words, “dedicated to demystifying an often overwhelming and intimidating shopping experience by providing educational content and well-designed, affordable, body-safe products.” While the brand offers quite a large selection of items, our focus for this guide is on Unbound’s water-based arousal gel, Jolt Gel. Cream and Cake Meds’ O-Cream Rx, Jolt Gel doesn’t contain any medications. Instead, this over-the-counter gel’s star ingredients are: L-Arginine and peppermint oil (due to its menthol content) can both promote increased blood flow through vasodilation.49 51 And damiana, or Turnera diffusa, is considered an aphrodisiac in traditional medicine.52 Studies are limited, but damiana appeared to help “sexually exhausted male rats” recover sexual behavior in a 2009 study.53 Of course, more research — especially on humans — is needed before we can definitively say damiana is effective. The other amino acid in the gel, L-ornithine, doesn’t have much research on it as a topical treatment, but it does appear to have some potential as a stress hormone reducer (for cortisol, specifically) when supplemented orally.50 But, as mentioned with damiana, more research is needed. Additionally, it’s important to note that Jolt Gel is not recommended for those with genital herpes, as the L-arginine content can trigger a flare-up. Jolt Gel can be purchased for $24 per bottle ($0.24 per pea-sized dose) either directly from Unbound or from its official Amazon storefront. At this time, we recommend purchasing through Amazon, as Unbound’s website doesn’t currently offer subscriptions. Even though Amazon’s subscription option, unfortunately, doesn’t come with a discount, it does let you receive regular shipments of Jolt Gel without having to remember to reorder. Additionally, throughout our time keeping an eye on these products, we found that the Jolt Gel on Amazon goes on sale rather frequently.

Side Effects and Risks

For example, at one point in early 2025, it was only $16.80 per bottle — that’s 30% off the regular price. But by the end of 2025 and heading into 2026, the price has returned to $24.

Neither purchase avenue accepts returns or refunds of opened weekend viagra products, but Unbound will accept returns of unopened, unused Jolt Gel within 30 days of purchase.

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However, as with all of the supplements mentioned in this guide, the potential effects will take time to appear — anywhere from a few weeks to a couple of months. Unlike the other options in our top picks, there’s a strange lack of transparency with some of the ingredients in the HerSolution supplement. On the Leading Edge Health website, the company lists the “HerSolution formula” as: This formula is further described as “a blend of herbals, amino acids, aphrodisiacs, and sexual nutrients.” We’re not entirely sure what a “sexual nutrient” is, but we do know that while the formula is, indeed, herbals and some other botanical ingredients used as aphrodisiacs, there aren’t any amino acids in HerSolution. Niacin (or nicotinic acid) can come from an amino acid, tryptophan, but it isn’t one itself — and that’s the closest thing we could find.31 But that’s not where the transparency issue lies; the main problem we have with HerSolution is Leading Edge Health’s confusing decision not to mention that this supplement contains two synthetic hormones: melatonin (5mg) and DHEA (25mg). The former isn’t the worst addition in the world (it may cause daytime sleepiness and headaches), but the latter can have serious health consequences; DHEA is not studied nearly enough to be worth an inclusion without mention.32 The amount of DHEA in HerSolution falls under the “possibly safe” category if you use the supplement as directed, and the other ingredients are all generally safe (with some decent scientific backing for helping sexual dysfunction), but an ingredient that the Mayo Clinic suggests avoiding seems worth a section on the product page.5 6 To be clear, we’re not saying that you shouldn’t try HerSolution if it sounds like something you’re interested in — it very well may be the most helpful option for you, and you should discuss it with your doctor.

How it Helps You Do It

We just want to properly inform you of the potential risks associated with the supplement since Leading Edge Health doesn’t try to. Interact with prescription medications (particularly those for mental health, including SSRIs, antipsychotics, carbamazepine, lithium, and valproic acid) Worsen psychiatric disorders and increase the risk of mania in people with mood disorders Increase the risk of hormone-sensitive cancers (prostate, breast, and ovarian) Lead to oily skin, acne, or hirsutism in women (male-pattern hair growth) viagra cream For more information on the potential drug interactions, you can find extensive lists from the Mayo Clinic and Mount Sinai. In terms of potential benefits of DHEA, the synthetic hormone may improve sex drive in older, postmenopausal women, specifically (not younger, premenopausal women). The results have been mixed, however.12 Looking at the rest of the ingredients, the outlook for trying HerSolution is a bit more positive. While we delve further into the nitty gritty details of these ingredients in our full HerSolution review, the following list breaks down some of the research.

CONVENIENT & DISCREET

Niacin: Can improve blood flow via the promotion of nitric oxide production.33 Hops extract: May help relieve hot flashes and increase libido via its potential to bind to estrogen receptors.34 35 Mucuna pruriens: Contains a precursor to dopamine, one of the neurotransmitters heavily involved in sexual arousal.17 36 Tribulus terrestris: “Significantly improved” postmenopausal patients' levels of desire and arousal, along with promoting orgasms and reducing pain from intercourse in one 2016 study. (And the dose in this study was 750mg per day compared to the 150mg in HerSolution. Ginkgo biloba: Can influence nitric oxide production.38 Epimedium sagittatum: Might increase sexual desire in postmenopausal women by promoting estrogen biosynthesis.39 Cayenne pepper: Acts as a vasodilator and can promote the release of nitric oxide.40 Melatonin: May improve sexual function in postmenopausal women.41 You can purchase HerSolution directly from Leading Edge Health, on either the company’s website or the product’s dedicated site (both are legitimate). Buying more than a one-month supply also gets you a free tube of HerSolution Gel, which retails for $59 (we discuss the gel in more detail later on). Here’s how the cost of HerSolution breaks down: Depending on whether you purchase from Leading Edge Health or from the HerSolution website, the shipping costs will differ. Amazon, in contrast, won’t accept returns at all for safety reasons.

Interested, but not quite ready?

Instead, this over-the-counter gel’s star ingredients are: L-Arginine and peppermint oil (due to its menthol content) can both promote increased blood flow through vasodilation.49 51 And damiana, or Turnera diffusa, is considered an aphrodisiac in traditional medicine.52 Studies are limited, but damiana appeared to help “sexually exhausted male rats” recover sexual behavior in a 2009 study.53 Of course, more research — especially on humans — is needed before we can definitively say damiana is effective. The other amino acid in the gel, L-ornithine, doesn’t have much research on it as a topical treatment, but it does appear to have some potential as a stress hormone reducer (for cortisol, specifically) when supplemented orally.50 But, as mentioned with damiana, more research is needed. Additionally, it’s important to note that Jolt Gel is not recommended for those with genital herpes, as the L-arginine content can trigger a flare-up. Jolt Gel can be purchased for $24 per bottle ($0.24 per pea-sized dose) either directly from Unbound or from its official Amazon storefront. At this time, we recommend purchasing through Amazon, as Unbound’s website doesn’t currently offer subscriptions.

Addyi (filbanserin)

Even though Amazon’s subscription option, unfortunately, doesn’t come with a discount, it does let you receive regular shipments of Jolt Gel without having to remember to reorder. Additionally, throughout our time keeping an eye on these products, we found that the Jolt Gel on Amazon goes on sale rather frequently. For example, at one point in early 2025, it was only $16.80 per bottle — that’s 30% off the regular price. But by the end of 2025 and heading into 2026, the price has returned to $24. Neither purchase avenue accepts returns or refunds of opened weekend viagra products, but Unbound will accept returns of unopened, unused Jolt Gel within 30 days of purchase.

Exploratory Phase 2b RESPOND Study, Completed in 2023

Amazon, in contrast, won’t accept returns at all for safety reasons. This no-return policy isn’t that out of the ordinary; it’s similar to the policies of Wisp and Cake Meds for their topical arousal products. Should be generally safe for healthy adults when used as directed Several ingredients have research suggesting potential efficacy Company fails to mention inclusion of melatonin and potentially risky DHEA Unsafe for those who are pregnant or breastfeeding DHEA may interact with medications, worsen mental health, and raise risk of mania Money-back guarantee requires minimum purchase of 2-month supply Potential results take at least a few weeks to months HerSolution is a female libido support supplement from the wellness company Leading Edge Health. Like VitaFLUX, it’s intended to help women and AFAB individuals with sexual dysfunction symptoms, like vaginal dryness, difficulty achieving orgasm, and low sex drive. This one-pill, once-a-day supplement may be more appealing to some who don’t wish to take six VitaFLUX capsules. This no-return policy isn’t that out of the ordinary; it’s similar to the policies of Wisp and Cake Meds for their topical arousal products. Should be generally safe for healthy adults when used as directed Several ingredients have research suggesting potential efficacy Company fails to mention inclusion of melatonin and potentially risky DHEA Unsafe for those who are pregnant or breastfeeding DHEA may interact with medications, worsen mental health, and raise risk of mania Money-back guarantee requires minimum purchase of 2-month supply Potential results take at least a few weeks to months HerSolution is a female libido support supplement from the wellness company Leading Edge Health. Like VitaFLUX, it’s intended to help women and AFAB individuals with sexual dysfunction symptoms, like vaginal dryness, difficulty achieving orgasm, and low sex drive. This one-pill, once-a-day supplement may be more appealing to some who don’t wish to take six VitaFLUX capsules. However, as with all of the supplements mentioned in this guide, the potential effects will take time to appear — anywhere from a few weeks to a couple of months.

What women are saying

However, it’s currently unknown how well it works on all ingredients, and the effect may be inconsistent on some.87 As with most supplements and medications, there are some safety risks to keep in mind. For Libido Lift Rx and Drive For Her, they include: Both products (and O-Cream Rx) are unsafe for individuals who are pregnant or nursing. Tadalafil can lead to headaches, indigestion, back pain, nasal congestion, hypotension, skin flushing, limb pain, nausea, dizziness, vision changes, hearing loss, and rashes.64 Tadalafil may interact with alcohol, alpha-blockers, antihypertensives, and other medications.64 Fenugreek (Libifem) may be unsafe for those with thyroid or hormone-sensitive concerns.88 89 Reishi may interact with medications for diabetes, blood pressure, and blood clotting.90 Saffron shouldn’t be taken by those with diabetes, hypoglycemia, low blood pressure, or bipolar disorder. It may also interact with sedatives, antidepressants, and more.91 Of course, the list above isn’t comprehensive, so you should always speak with your doctor before adding a new supplement or prescription to your routine. It’s worth mentioning that Cake Meds For Her can’t be shipped to Alabama, California, South Carolina, Guam, or Puerto Rico due to restrictions.

Increased genital blood flow

This means that those territories can’t get Libido Lift Rx or O-Cream Rx, but they can still get the Drive For Her supplement. In contrast, Wisp is able to prescribe medications in all 50 U.S. states, so you can get OMG! Cream no matter where you are viagra daily in the country. The chart below breaks down the pricing details for Libido Lift Rx, Drive For Her, and O-Cream Rx (regular and extra strength).

Side effects

As you can see, Cake’s prescription products can’t be purchased on a one-time basis. This means that you’ll have to sign up for a recurring subscription if you’re interested in either of those. Drive For Her, on the other hand, can be purchased either way, and it’s covered under the company’s 30-day satisfaction guarantee. Around 100 treatments per bottle if used as directed Peppermint oil and damiana may promote arousal Should be safe for pregnant individuals (still check with your doctor, though) Not recommended for people with genital herpes due to L-arginine content No guarantee available and refunds are only for unopened products Some people may not like the warming, yet cold and minty sensation Unbound (also known as “Unbound Babes”) is a sexual wellness company that is, in its own words, “dedicated to demystifying an often overwhelming and intimidating shopping experience by providing educational content and well-designed, affordable, body-safe products.” While the brand offers quite a large selection of items, our focus for this guide is on Unbound’s water-based arousal gel, Jolt Gel. Cream and Cake Meds’ O-Cream Rx, Jolt Gel doesn’t contain any medications. Unlike the other options in our top picks, there’s a strange lack of transparency with some of the ingredients in the HerSolution supplement. On the Leading Edge Health website, the company lists the “HerSolution formula” as: This formula is further described as “a blend of herbals, amino acids, aphrodisiacs, and sexual nutrients.” We’re not entirely sure what a “sexual nutrient” is, but we do know that while the formula is, indeed, herbals and some other botanical ingredients used as aphrodisiacs, there aren’t any amino acids in HerSolution. Niacin (or nicotinic acid) can come from an amino acid, tryptophan, but it isn’t one itself — and that’s the closest thing we could find.31 But that’s not where the transparency issue lies; the main problem we have with HerSolution is Leading Edge Health’s confusing decision not to mention that this supplement contains two synthetic hormones: melatonin (5mg) and DHEA (25mg).

If you're tired of uncertain quality and unproven options, you're not alone.

What is FSAD?

What causes low libido in women?

The former isn’t the worst addition in the world (it may cause daytime sleepiness and headaches), but the latter can have serious health consequences; DHEA is not studied nearly enough to be worth an inclusion without mention.32 The amount of DHEA in HerSolution falls under the “possibly safe” category if you use the supplement as directed, and the other ingredients are all generally safe (with some decent scientific backing for helping sexual dysfunction), but an ingredient that the Mayo Clinic suggests avoiding seems worth a section on the product page.5 6 To be clear, we’re not saying that you shouldn’t try HerSolution if it sounds like something you’re interested in — it very well may be the most helpful option for you, and you should discuss it with your doctor. We just want to properly inform you of the potential risks associated with the supplement since Leading Edge Health doesn’t try to. Interact with prescription medications (particularly those for mental health, including SSRIs, antipsychotics, carbamazepine, lithium, and valproic acid) Worsen psychiatric disorders and increase the risk of mania in people with mood disorders Increase the risk of hormone-sensitive cancers (prostate, breast, and ovarian) Lead to oily skin, acne, or hirsutism in women (male-pattern hair growth) viagra cream For more information on the potential drug interactions, you can find extensive lists from the Mayo Clinic and Mount Sinai. In terms of potential benefits of DHEA, the synthetic hormone may improve sex drive in older, postmenopausal women, specifically (not younger, premenopausal women).

• Online pharmacies like Superdrug Online Doctor offer private consultations.
• Boots Online Doctor provides a similar service for discreet access to treatments.
• LloydsPharmacy Online Doctor allows for private prescriptions following an assessment.
• The NHS provides treatment primarily for underlying causes like depression or menopause.
• Private clinics, such as The London Hormone Clinic, specialize in women's health.
• Costs for private prescriptions vary significantly, often £50-£100 per month.
• Always ensure any online provider is registered with the General Pharmaceutical Council.

The results have been mixed, however.12 Looking at the rest of the ingredients, the outlook for trying HerSolution is a bit more positive. While we delve further into the nitty gritty details of these ingredients in our full HerSolution review, the following list breaks down some of the research.

Niacin: Can improve blood flow via the promotion of nitric oxide production.33 Hops extract: May help relieve hot flashes and increase libido via its potential to bind to estrogen receptors.34 35 Mucuna pruriens: Contains a precursor to dopamine, one of the neurotransmitters heavily involved in sexual arousal.17 36 Tribulus terrestris: “Significantly improved” postmenopausal patients' levels of desire and arousal, along with promoting orgasms and reducing pain from intercourse in one 2016 study. (And the dose in this study was 750mg per day compared to the 150mg in HerSolution. Ginkgo biloba: Can influence nitric oxide production.38 Epimedium sagittatum: Might increase sexual desire in postmenopausal women by promoting estrogen biosynthesis.39 Cayenne pepper: Acts as a vasodilator and can promote the release of nitric oxide.40 Melatonin: May improve sexual function in postmenopausal women.41 You can purchase HerSolution directly from Leading Edge Health, on either the company’s website or the product’s dedicated site (both are legitimate). Buying more than a one-month supply also gets you a free tube of HerSolution Gel, which retails for $59 (we discuss the gel in more detail later on). Here’s how the cost of HerSolution breaks down: Depending on whether you purchase from Leading Edge Health or from the HerSolution website, the shipping costs will differ.